Please post your opinions about the Osprey when you get a chance to use it in real world packing/travel.
I'd have bought one, too, but I'm what my dear wife calls "unnecessarily, perhaps stupidly, bag-rich".
I've had an Osprey Porter 46 since about 2011, and it's my go-to carry on. Since mine is so much older, it doesn't have the laptop compartment or organizational panel in the front of the bag, but otherwise, it doesn't seem that different than the current versions. I've used it for everything from personal weekend trips to 10-day work trips and it's managed each with aplomb. Not to say it couldn't happen, but unlike my rolling carry-on from another company, I've never had it questioned by airline staff for size or weight, even on European carriers that are a bit stricter. I've even carried it on smaller, regional jets with tiny overhead compartments and either stuffed it under the seat in front of me (I'm short) or in the overhead bin if I pack it accordingly so I can use the cinch straps to cinch it down small enough to fit.
It can hold a lot of clothes, and there always seems to be another nook I can stick another small item in. I like the firm sides that provide protection for the contents of the bag but still have some give if you need to shove the bag in a tight spot. Mine has two interior pockets, one along one side of the bag and another on the front panel of the bag, and those come in handy for smaller items, or in the case of the one on the front panel, tucking in receipts and whatnot for the trip.
The backpack straps are comfortable enough for walking through airports, trips on public transportation to lodging, etc. It's nice to have my hands free in those situations. On the rare occasion I've had to check the bag (such as when bringing back more liquids than allowed through security), the straps have tucked away easily to ensure they don't get caught on a conveyer belt and the bag's been none the worse for it. I tucked the hip belt back into its pockets shortly after getting the bag and haven't used that since.
In short, I love this bag! I'm not sure I'd really use the laptop sleeve and front organizational pockets on the newer versions, as I usually keep my laptop or tablet, wallet, passport, etc. in a separate bag that's easier to take with me to the restroom, etc. but who knows. I might learn to love those, or find different uses for them.