Thanks to Pam and BethFL, I received the Osprey Ozone 42L monopole 2-wheeled carry-on bag for my birthday (the one that is currently on sale at Osprey). For clarity, they didn't give it to me, but their suggestions were passed along to the DH ;-).
I just finished packing it for a 2-week trip to Boston for the Thanksgiving Holiday. This is the first wheeled carry-on bag I have owned and it was interesting to pack. It weighs a pound more than my extra-small Osprey Fairview 38L backpack and as the names suggest, should hold 4 liters more. I'm not sure that in real-life packing it does. As Pam mentioned in her thread, https://community.ricksteves.com/travel-forum/general-europe/anything-travel-related-on-your-christmas-wish-list, the design of the bag leaves odd-spaces which I filled with toiletry related items. For a trip of this length I would ordinarily pack 5 tops, one bottom, 5 socks, 5 undies, toiletries and 1 pair of shoes. For this trip I had to add dressy pants and a sweater, a packable down sweater, hostess gifts for friends and family, and a laptop and charger. All packed I could lift the bag over my head but not very comfortably. I'm 5'2" and since I'm vertically challenged assistance is frequently offered. But I don't like to - or want to - assume that it will always occur. So I moved the laptop and charger to my personal item bag and that made a surprisingly large difference.
I brave SeaTac tomorrow. Wish me luck. Oh, and Happy Thanksgiving to all. I am grateful for the opportunity to travel and to share it with friends.