I do understand what you are saying Cindy, but I still find it a pain in the neck to unfold the bundle to get to a shirt that is on the inside. In a cube (and I have found that for the shirts I take folding flat in the cube works better) I don't have to take the cube out of the suitcase, just unzip, pull out the new shirt, tuck in the old one and I'm done and I still have everything in my suitcase.
Cubes can add weight, altho the silnylon ones are less than 2.2 oz for the entire set of 3 (sm/med/large) so that adds a negligible amount of weight to your overall total. Their compression cubes which aren't actually compression but just an extra zipper to smash them down are heavier due to the weight of the second zip. I have them but would not buy them again.
For me, as far as organization goes, the visual of the cubes and what's in them is easier for my brain to process. I can take a quick look and see 2 unders, 1 bra, pjs, socks, compression shorts in one small cube. I can easily see if I've got all my shirts/cardie in the larger cube.
It does come down to practicing several different methods to see what works for each individual so there is no right way for everyone. As I said I started out this way, (with minimal clothing) and found I like a different visual look to the organization of my suitcase.
editing to add: Rankster, yes, the last night in Austria I packed one small cube with clothes for my 2 nights in Venice and it was easy to put that cube plus my toiletries in my tote bag to carry in to Venice. I did the same thing for my nights in Monterosso.