We recently returned from our holiday in York, Hexham (for Hadrian's Wall), Oxford and London. Thought I'd share my packing list in hopes it might be useful to someone. I decided what to take based on historical weather info and past experiences. I wore everything repeatedly and washed twice at our apartments. My color palate was black, grey, white and pink. I wore some of this stuff on the plane. Pants, turtlenecks and sweaters are Land's End.
2 pair black jeans (Wear one, wash one. They dry quickly on heated towel racks.)
4 lightweight (layering) turtlenecks
1 grey cotton cardigan
1 pink crewneck cotton pullover sweater
2 underwear (wear one, wash one Ex-Officio brand)
2 bras (ditto on Ex-Officio)
1 compression socks
1 wool socks (socks were also in the wear one, wash one inventory)
1 slipper socks from hospital to wear as slippers in apartments/hotels. Tossed before heading home.
Coldwater Creek knee-length raincoat with button-out wool lining
Hat and gloves (especially happy to have these at the Wall and a couple of mornings in York; but didn't use them elsewhere)
1 set Cuddle Duds thermals (also wore these as pj's, borrowing one of my husband's t shirts if it was too warm for the thermal top)
Ecco walking shoes
Basic toiletries (sunscreen, moisturizer, ibuprofen, polysporin, bandaids, etc) - first stop in York was Boots for toothpaste, etc
Spare glasses
Cross-body travel day bag/purse with lots of pockets (eBags)
Lysol wipes for tray table, apartments and hotel rooms upon arrival
Travel umbrella (which was used only once, taking it needs reevaluation)
In my personal item (a messenger bag), my biggest problems (in terms of bulk and weight) are medications and disposable contact lenses. Both decrease over time but start heavy. I carry broken-down guide books because we like to have them with us each day when touring; I'm never happy carrying my heavy iPad around. I am still, sadly, largely wedded to paper for tickets, reservations, and confirmations, which also decrease over time. Phone, iPad and cords were also in the bag of course. All in all, I was happy with the list, although it will be a while before I wear any of it again.