Here's my packing list:
Layers are what work. Wear on plane: black cotton-blend pants, long sleeve turtleneck/T-shirt in winter, or short T in summer, and a long-sleeved or 3/4 sleeve "big shirt" {button up that can look a bit like a jacket}, Windbreaker/raincoat or winter coat with hood, good walking shoes.
In carry-on:
2-3 pair black or khaki cotton-blend pants (I am allergic to wool and rather hot-natured)
3-5 T-shirts/turtlenecks (sleeve length depends on season) I tend to take red, cobalt, purple or black tops.
1 additional "big shirt"( in summer, one short sleeve and one long or 3/4- in winter, both long),
I usually take a couple of scarves -everything coordinates with everything else.
3-5 bras, at least 7 pair undies (often enough for entire trip) same with socks
1 pair pjs if desired
Optional - a sweater/cardigan or fleece
Gloves, hat or hooded scarf (in fall and winter)
extra shoe liners
phone, charger, adapter plug
3-1-1 bag with deodorant, perfume, shampoo, lipstick, chap stick, toothpaste, etc.
another quart baggie with eye shadow, blush, face powder, talcum powder, comb, brush, tweezers, razor, clippers, small baggie with laundry soap,etc. , "feminine supplies" if needed
wash cloth in a baggie,
Everything is organized using ziplock bags.
In my day pack (some trips it has been a back-back style, others a cross body style), I take hand wipes, stain wipes, first aid "kit" in a baggie- band-aids, small packets of Neosporin, dental floss, Advil or Aleve, Benadryl, Dramamine, Nyquil gel capsules, etc., - sewing "kit"(various colors thread wrapped around a small piece of cardboard, 2 needles, buttons, safety pins), prescription medications, medical info sheets, copy of insurance info, paper & pen, umbrella,
Hubby gets by with a bit less. He wears dark Dockers style pants and a polo in summer, a long sleeve shirt in winter. He packs 1 or 2 pairs of dark or khaki colored pants, 3 or 4 shirts, with at least one button up collared shirt, 3 pairs of socks, 3 pairs of undies. His 3-1-1 bag with deodorant, cologne, toothpaste, shampoo, etc. He takes the camera & charger, extra memory cards for camera, his phone and charger and plug adapters/converters.
We are old fuddy-duddies and each wear a waist bag, too (fanny pack, but don't use that term in the UK...LOL!).
We each take one of Rick's carry-on suitcases and a day bag. Also, we each pack a collapsible bag in case we buy a lot of things- though we don't do that as much as when we first started.
Our bags weigh less than 20lbs each, hubby’s sometimes less than 10#s. Our bags can be worn as back-packs or on the shoulder or carried in hand. Easy to get on and off trains, and don't take up much room overhead or under the seat.
Oh- don't take a blow dryer, curling iron, straightener, etc. Even with a voltage converter and plug adapter they often don't work well 'over there'. Style your hair simply and use the blow dryer provided by the hotel.