I have traveled extensively through Europe in my 60s and 70s (and I'm a short, non-athletic female) with suitcases between 24" and 25" high including wheels and handles. I think I head out with a bag weighing over 30 lb.; the weight drops through the trip.
I manage (so I assume you can), but I don't recommend it unless you truly have no option. It is a struggle for me to get my bag onto a train quickly (on some trains you must go up three very narrow steps) or up a flight of stairs if a train station (or hotel) has no elevator or escalator. There is no hope of my lifting the bag above about waist height, so I have to remain in the vestibule of the rail carriage to babysit the bag if I can't find an accessible place to store it. That happens fairly often on busy trains during peak travel season (France in August...eek, and Belgium has a lot of rail carriages with only over-seat racks).
Intercity buses are a great deal easier. I can easily lift my bag one foot off the ground to get it into the luggage hold.
I've never really worried about luggage theft, but I suppose that's mostly because my suitcases have always been inexpensive and I don't wear jewelry or stylish/expensive clothing. I just don't see why a thief would be interested in my luggage as opposed to the much better-looking bags others use. Still, I am careful to carry electronics, medications and other critical items in a packable tote bag that stays with me on the train or bus.
Loss of a wallet or a smartphone is a much more likely event than luggage theft, though I believe pickpocketing is somewhat less likely in Germany than in some other countries. But then, I was pickpocketed in Veliko Trnovo, Bulgaria, so you can never let your guard down.