https://www.gov.uk/foreign-travel-advice/moldova
*Edit to include U.S. Level 2 advisory: https://travel.state.gov/content/travel/en/traveladvisories/traveladvisories/moldova-travel-advisory.html
Barb, there are supposed to be some really nice wineries in Moldova. I would definitely head for a day to one of those, given the chance. I’d want a driver, if I did that, though. (I figure that would not be difficult to find - plus I have seen some GYG type trips advertised). I would also love to see some of the monasteries in the non-Transnistria part. You could take a day to drive to Chisinau with stops, spend a day there, then take a day with stops to drive back. And Iasi itself would occupy a full day - there’s a ton of history there.
However, you could also drive to Targu Mures (where I haven’t been yet) or Sighisoara - you could visit some of the fortified churches in that area. Neither of those is a short drive, given the roads are smaller and narrower and more tiring. Either town would be a full day each way if you include a lunch stop and one sightseeing stop. So the same kind of 3 day, 2 night exploration.
One tip I might offer for any drive would be to plan ahead for potential lunch/bathroom stops. They are not as ubiquitous as some places I have been.