Quite a few thanks to Turkish Air. Currently they fly to a half dozen or more US airports and over 100 European destinations. This probably isn't real current, but gives you an idea: https://en.wikipedia.org/wiki/List_of_Turkish_Airlines_destinations
Settling it with a good carrier has made decision making easy and pulling the cord on the trip a lot easier too.
Friday after work (Turkish Air #34 out of Houston at 8:50 pm) then with a 1 - 3 hour connection in Istanbul I can reach more places in Europe (and the world) than any other airline serves.
Saturday, recover from Jet Lag but always the evening out.
Sunday, Party
Monday, Party
Tuesday, Party
Wednesday, Party
Thursday, Party
Friday, Party
Saturday, Party
Sunday Turkish Air #33 arrives Houston at 7:00 pm.
Book a few months in advance and the fare to is $600 to $800. So prorated, that's $100 a night or less. Hotel doesn't have to be more than $100 a night. On the ground expenses? I sort of love Eastern Europe so I dont spend any more than if I were home.
I've been on no less than 50 Turkish Air legs over the last 5 years; never canceled, never so late I missed a connection. Parking in Houston is $5 a day. Similar departure times out of Chicago, JFK, Los Angles and I think a few others.
Then once you get comfortable with the concept; my last fast trip was:
Friday depart Houston
Saturday arrive Budapest (of course)
Sunday, Monday, Tuesday, Wednesday; party in Budapest
Thursday a morning discount flight to Odesa which was $65 non-stop in about 90 minutes. Some of my favorite other side trips have been Sarajevo and Podgorica for a few days of fishing in the mountains. Here Budapest works because its a hub for Wizzair which flies to all sorts of wonderful places, cheap and direct.
Thursday afternoon, Friday, Saturday on the beach (or fishing in the mountains)
Sunday; head home (about half the time I stay till Monday)
Oddly enough that open-jaw can be $50 less expensive than a simple RT to Budapest which almost pays for the Wizzair Flight.