I do think every place has something of interest if one decides to look for it. That said, the only places that come to mind for me are driving across featureless Kansas and the high point was the Giant Prairie Dog statue. And then there is Reno. What a bizarre place! I found it sad in many ways, the color schemes in the hotels were way out in left field, and what's with all the bowling alleys there? Thank goodness they have "Reno 911" to lighten the place up a bit. Could not wait to leave there.
The only place in Europe that comes to mind, is Rüdesheim. The only saving grace is the chair lift that takes you to the most marvelous view of the Rhein. Other than that, it is just one souvenir shop after another, with souvenirs made in China.
I like all the other somewhat under rated cities, like Milan, Brussels, and of course Frankfurt. You have to try just a little bit harder to find the places of interest, then once you do, WOW, the city becomes fascinating. I like finding the odd places. I enjoy going back in our harbor district, especially at night as the lighting is fantastic, or walking the neighborhoods of a city, finding little churches, admiring the interesting balconies or courtyards or old doors, and finding unique stores. I would much rather do that then go to one museum after another. All of these cities have wonderful histories, but you do have to research it a bit.
Living here does give me a different viewpoint, but it makes me appreciate what we have too and I thoroughly enjoy every place we go.