I have lived overseas for 9 years as well as traveled a lot since retiring 15 years ago.
I always plan to visit places that are relatively close together to avoid wasting time traveling between places. Also, it saves money.
We visit a few places that we have visited before, but mostly try to visit new places.
For example, last year we did a great tour of Northern Spain and Southern France, starting in Barcelona, where we have visited three times before. However, we did visit some great places other than that, Carrassonee France and the Bordeaux region of France, then the Basque region of Spain before ending in Madrid, where I had been once.
Also, I had done Egypt in 1985, but my wife had not, so we did it with the Nile cruise and tour of other great places, also doing Abu Simbel, that I had not done before. I enjoyed seeing those same places again.
One thing that I discovered was the Egypt had vastly improved its infrastructure, with more modern highways. Also, it looked significantly more prosperous than when I visited in 85.