To answer your original question, there are flights from Germany to SFO connection on the east coast. I found one connection via USAir on Expedia,
MUC 12:15 - PHL 3:20
PHL 5:54 - SFO 9:14
I used Expedia and "Multiple Destinations" rather than one-way. I used Philadelphia as the second destination and filtered for USAir because I know they fly through Philly. USAir is not my favorite airline, nor is PHL my favorite airport. I believe United flys through Newark (EWR) as well as Chicago (ORD), but Chicago would be a longer first leg. Also, flying out of Frankfurt (FRA) would shorten the first leg.
To shorten the leg from Europe, you could book Icelandic Air via Reykiavik. The stop in Iceland, which is shorter than to the east coast, but they don't fly to SFO, so you would have some more stops to get to San Francisco.