Is the Provence Countryside safe for Black Americans?

You are worrying needlessly. At any given time, in any given place/country you could run into racist behavior but France s very low on the list of likely places for that.

I think you're more likely to find that sort of behavior in the US rather than Europe. For one thing, multi-racial couples are more common in Europe than here.

Your trip sounds wonderful, by the way! I'm sure you will have a fantastic time!

Agree with others who have posted ... and your itinerary sounds absolutely wonderful.

Have you considered one or even two weeks of 'self-guided' cycling? Regular or e-bikes. We were in France for 4 weeks last May/June and e-biked two of the four. Cycled the Dordogne (one week) and the Loire (one week) from Blois through Amboise, Tours, Azay-le-Rideau, Chinon and Sarlat. https://community.ricksteves.com/travel-forum/trip-reports/fabulous-tour-de-france-2-weeks-on-foot-and-by-train-2-weeks-by-e-bike. One site that offers a wealth of information about MANY MANY possibilities from many different vendors throughout all regions in France is https://www.freewheelingfrance.com .

The vendors arrange for the bikes, hotel stays and luggage transfers. Plus, they are availbale for phone consults in case of problems. All you need to do is bike from hotel to hotel; chateau to chateau (or other site, village, cro-magnon cave, winery, etc.). (We did have one flat tire to deal with, but fortunately that was in a town, so we just walked the bike over to a bike shop.)

BTW, apropos your original query, we were surprised to see different sad references to France's role on the slave trade ... something that is being acknowledged and faced. We first learned about this at one of the Bordeaux wine museums ( https://www.museeduvinbordeaux.com/language/en/home-3/ ), where we learned that wine played a role in the 'triangle trade.' See also https://www.nouvelle-aquitaine-tourisme.com/en/bordeaux/colonies-the-writing-on-the-walls (Bordeaux) and https://memorial.nantes.fr/en/nantes-the-slave-trade-and-slavery/ (Nantes's moving memorial and history lesson)

As a white woman married to a white man, I have never been in your shoes. I would never suggest that you'll be just fine. I do not know that you would. I do like to look at facts, though, and wonder where you might find them. (Probably why you came here!) I wonder if the communities that you're looking at visiting have any stats on crimes/harassment.

As a retired marriage and family therapist, I saw several couples who had been victims of harassment. They were bi-racial--white woman and black man. They were harassed by white men who took umbrage at a black man being with a white woman and became menacing to those couples. So, I understand your concern. Statista is a source used by many. I think you have to pay for it, though. I hope you have a wonderful, safe trip.

No relevant personal experience, but I wanted to point you to a blog/YouTube channel The Francofile by a young American couple who did master's degrees in France, now live and work there. She's white, he's black.
My guess - and I don't pretend it's any more than that - is that people are perceived as Americans first and foremost, regardless of color.

I would agree that mixed race marriages are more common in France than in the U.S. Just today, I was shopping at a market in Normandie and I encountered one couple with a white husband, a black wife, and a brown child, and shortly after walked past a black husband, white wife, and two brown children. It's commonplace. There's not zero racism in that regard, but I believe it's less than in the U.S.

I will note this, though: I have encountered racism, or at least bigotry, against North African immigrants on more than one occasion. I distinctly remember a dinner party in a suburb of Lyon where one of the guests, a nun, made several negative comments about "dark" people coming to France. At first I wasn't sure what she was referring to, but as she went on it was clear she was talking about Muslims from North Africa. It may have been more religious bigotry than racial bigotry, but it was both surprising and uncomfortable. I'd never interacted with a nun before, and I suppose I naively had higher expectations.

I doubt if you'll have any bad experiences, but I'm white so can't speak with authority. Southern France has a lot of non-white residents, native and immigrant, whose families came from North or West Africa, where France had colonies. Sadly, it's possible to encounter racism anywhere, but I (again as a white guy) doubt if you'll find anything in France worse than in the US, and I'd guess (see above, white guy) the overall climate will be better. And you'll be perceived as American tourists anyway (a mixed blessing). Hope you have a wonderful trip.