Is there a website where one could easily determine which airlines provide service between specific cities? I used to start with Expedia, or Orbitz for an overview (e.g., NYC to Prague) and then research each carrier myself. But I know not all carriers choose to list with these sites, and I wonder what I am missing, and how I can research fares most effectively. Air cost, for one reason or another, is the bone that sticks in my throat the worst when it comes to making these trips. Thanks
In addition to the advice given above, I find that this website is often useful: Airline Route Maps It's not always 100% accurate or up to date, but works as a good starting point.
Try skyscanner.com for a wider variety of carriers, especially within Europe.
I use a combination of Kayak (kayak.com), ITA Software (http://www.itasoftware.com/), and Which Budget (www.whichbudget.com). It takes a lot of patience and persistence to find a good airfare these days!
Another trick I used for some smaller airports (in the US and abroad) is to go to the airport's Wikipedia webpage. A lot of times they list different commercial carriers that fly into that airport along with where they fly to/from. That's how I found out that Lufthansa has direct flights from Frankfurt, thus making my trip a couple of years ago with only one layover from SEA. It's also how I found out that there's a direct flight from Lisbon to Sevilla.<br><br> Here's an example using Porto's Airport
You can also go directly to most airport websites to find out which airlines service the airport. Pam
If you really run into a preferred open jaw route that is not serviced by the same airline (I had it with an CID to Amsterdam...Manchester, UK to CID) try a consolidator like AirGorilla or AirlineConsolidator. They can piece together non-partenered airlines to get you a decent priced ticket.
Thank you to all posters for the informative responses! This will be a great help. Thanks again.