I have been to Italy several time. In June we're renting a villa in Tuscany (near San Gimignano). Afterward we are going on to Nice, France. I keep checking airfares and will go with the cheapest one from JFK, but has anyone had any experience flying into Genoa?
Chances are that Summer, 2014 is going to be expensive on airfares to Europe. You don't say where you're flying out of.
Unfortunately, there are no direct flights from the U.S. into Florence. Delta flies from New York JFK into Pisa. There are no direct flights back to the U.S. from Nice.
I've been looking at http://matrix.itasoftware.com/ for the "multi city" section, which is open jaw into one city and out of another.
We're going into Budapest and home from Prague in 3/25-4/8/2014. Flights are running $1012, and they've been consistent in recent months. Last time I checked, flights increase about $200 for the Spring season on 3/29/2014. Then, they go up again the end of May.
I read about a one day sale last month in the Atlanta newspaper travel section for $728 on United. Needless to say I jumped on it.
My best suggestion is to research airfares online for a couple of weeks to come up with a baseline price. You can sign into some websites like airfarewatch.com that will notify you of any price drops. If nothing shows up, come back after the first of the year to purchase your ticket.
London is often a reasonably priced destination from some larger U.S. cities. An option would be to fly there and take EasyJet.com out of Gatwick to and from Pisa and Nice.