Train pass or individual tickets

How are you getting from Strasbourg to Munich? From what you've shown, I'd buy the Paris-Strasbourg leg online now to get the best price. Since you're spending a lot of time in Switzerland, look into getting a Swiss pass from SBB (Swiss Railway). This will give you additional discounts on private railways (Berner Oberland Bahn, Zermatt, Gornergratt Bahn) plus lake steamers.
2nd class is perfectly comfortable on TGV.

I stopped buying train passes when I stopped doing long travel legs. I haven't priced them recently to give you a good break even point. Generally, the pass is more expensive than all but the longest point to point train tickets. The main advantage of the pass is the hop-on-hop-off ability and it often covers local transit as well (but only on days where you are "on" your pass). If you use either or both options regularly, they can be valuable. If you play with the prices, it may be worth having a pass for some of your travel days but point to point on others. You may also qualify for a discount that may make a pass a better deal, but I don't know of any. As far as I know, if a train requires a reservation, you need one whether you are traveling on a pass or point to point ticket (extra cost for either option). I've traveled both first and second class. For me it's first class when I'm on business (because someone else is paying) and second class when I'm traveling on leisure (because I'm paying). First class is slightly nicer, not enough nicer IMO, however, to justify the extra expense. First class can be quieter and a little more private. The difference isn't close to flying first class vs. coach - or even business class vs. coach preferred seats.

Pricing this out, it may be advantageous to buy "half fare" cards from Swiss Rail. They cost 175 chf each (2nd class), good for one year, so then you pay half fare for all the tickets inside Switzerland. You still need reservations on many trains, especially the Glacier Express. So a straight pass would not pay for itself.

Two points - If you use a Railpass which includes France so that you can have your Paris - Strasbourg less than three hour trip covered, you will have two difficulties: on the TGV (fast French train and the one you will use) mandatory passholder reservations are like hens teeth, rationed and rare - and more money on top of your expensive pass. Why expensive? Because the Selekt passes which include a few countries are not being participated in by the French this year which will force you into a Global Pass which they still are. Plus you still need to pay for that elusive bl**dy reservation which is included in point-to-point tickets available far in advance for quite cheap. Secondly - You're going to Interlaken but not going up to the mountains? I'd suggest using the train from Interlaken Ost which goes up to Lauterbrunnen and has connections onward to the Schilthorn or Jungfrau, or at least part way up to the car-less villages.

Dear gentlemen – thanks so much for your input and advice! We are driving from Strasbourg to Munich over a 7 day period, then picking up the train from Munich. In terms of car hire, I will search other posts regarding this, particularly who/where to hire a car from in Strasbourg, where to drop car in/near Munich prior to our train travel, and sights to see along the way. Regarding Paris/Strasbourg rail, yes, we will buy a point-to-point ticket. 2nd class TGV would be OK, but I'm a 6ft tall medium build gal ... is there enough legroom for me (it's all about ME lol) in 2nd class? And, since we have 2 x 7 hour subsequent train journeys (Munich/St Moritz, then Glacier Express), are we better to go 1st class? A Sydney-based Swiss travel agent verbally advised yesterday that it would be better to pay for the rail sector/s from Munich to the Swiss border, then a Swiss Flexi Pass may be a good option for some or all of the next 7 days of travel and sightseeing. I understand that reservations are required for some trains, and we are happy to do this. Interlaken – yes, we do want to go up the mountains. Our initial thought was to catch the train from Zermatt to Interlaken and do day trips from there. But other advice has suggested that we stay at/near Wengen so we can go up the mountains. Nigel, thanks for your suggestion about Interlaken Ost – will investigate.

Interlaken and do day trips from there. But other advice has suggested that we stay at/near Wengen I have done both. Advantages of Interlaken: One less train change with luggage.Close to the boat landings for Thunersee (Interlaken West - next to the station) and Brienzersee (Interlaken Ost - next to the station) if you want a rides on the lake steamers.The supermarkets are larger and right next to the station - MMMigros at West, Coop at Ost.When you want to get away on the last morning you are closer to the main line station. Disadvantages of Interlaken: It is a big town, with big town traffic, big town parking problems, big town crowds.It is by no means in the mountains - you have to go to them. Advantages of Muerren (or Wengen - although I have visited Wengen I have never stayed there) Because tour groups usually stay in Interlaken and Grindelwald and independent travelers more in Muerren, Wengen, Gimmelwald, and to a lesser degree Grindelwald, our experience is lower prices in Muerren than Interlaken if you play your cards right.The small Coops (Muerren and Lauterbrunnen) have pretty much what you need, just lesser variety.In Muerren and Wengen you feel that you could reach out and touch the mountains - indescribable.In Muerren, Wengen and Gimmelwald (to a lesser degree Grindelwald) you can leave your hotel room, walk around the corner and have started your hike. 3 metres from the door and you are on the trail.No cars.Many fewer people.