Rent a car on Malta

Yes, just use google and you'll find them. Same with Gozo ferry - it will tell you if cars are allowed on it and how much it costs.

We recommend renting through Auto Europe (www.autoeurope.com) and it looks like Avis has a location there. You could compare rates directly on Avis' website versus Auto Europe, which is a consolidator and typically cheaper.

I would like to refer you Sicily Tour Services. They have fine packages for your trips anywhere in Europe.
http://www.sicilytourservice.com/

You do know that they drive on the left as in the United Kingdom, Ireland, and other countries with a British history.

Malta is small, the roads are narrow and there are many cars and buses, so traffic can be very slow and driving may be very stressful.