Thanks to all for the feedback.
My first trip to Europe was in 1980 and I have returned something over 40 times since, traveling independently and mostly solo, getting around mostly by rail (with a few ferries, buses and planes tossed in). I learned fairly early that Rick was right, pack light, but these circumstances are peculiar for two reasons. First, I will be visiting friends in Prague, where I have a standing offer of a room in the suburbs. To give them a break, I generally go off on my own for a week or more, leaving the large bag (and all the presents it held!) with them and living out of the carry-on a la Rick. Normally I'd fly straight in, but the desire to minimize exposure to COVID and the craziness of airfares and "nickle&dime you to death" pricing policies led me to the plane/train plan.
The second factor: Trying to find a window that would work around my friends' schedules, I intended to embark less than a week after scheduled cataract surgery - and lifting >10 lbs on the way over would be verboten. I could probably persuade friendly hands to help get the checked luggage onto the plane and off the baggage carousel; I could roll it to the long-distance rail station at FRA, and organize help getting it on there and off again at Prague. But. The bottleneck was one (or two) very tight rail transfers en route. I doubt I could enlist help fast enough to navigate (e.g) the 22-platform Hauptbahnhof at Nuremberg in the 10 minutes available. Checking the large bag through on the rail leg, with DB doing the heavy lifting, would have been the ideal solution - even if it was delayed a day or two I'd be able to live out of the carry-on a la Rick.
I do appreciate the DHL suggestion, as I'm thinking of bringing some tableware and glass (MORE presents!) home from Czechia , and I'll bang that option against whatever the vendors would charge to ship, or what a second checked bag would cost; I should have time in-country to investigate the options (since I've seen nearly everything worth seeing in the region, and one can only drink so much beer, however excellent...)
Let me offer a couple of suggestions for bringing stuff home from Prague: (1) The best deals I've found on Bohemia glassware (not as spiffy as Moser, but visit the Moser store in the Black Rose shopping center on Na prikope, enjoy the beautiful items [I call it the "glass museum"], & check the prices - if I can't afford their wares, your probably can't either) were at the Kotva department store (late-Communist-futuristic building about 150 km north of Namesti republiky, same side as Obecni dum). Fourth floor IIRC. Same items as in the Bohemia store near Narodni trida and Wenceslas square (look there first if you wish), but discounts of 20-40%. Kotva, however, didn't ship stuff when last I looked. (2) Trying to get the VAT refunded for items you're taking/shipping home is a pain; I tried it once and after hassling the process on the morning of departure got something like $5 back, If you're tricking out an entire house it might be worth it, but... (3) Dark-red Czech garnets are lovely (I've seen them processed and mounted in a visit to Turnovo) but my friends (who are/were geologists) warn that a lot of what's on offer is actually lower-quality stones from India. How to tell them apart? Beats the hell out of me, I was a mathematician in a previous life... But hey, if you like their look and the price is fair, why quibble?
Happy trails to all. Slava Ukraini!