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Florence to Prague

any suggestions on how to get from Florence to Prague reasonably? Traveling with my daughter in late August/early September and wonder where to stay in Prague...B&B or hostel?

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You have quite a travel itinerary. Edinburgh/Rome and now Florence/Prague. Prague is 700 miles from Florence. By train, you are looking at 18.5hrs-21.5hrs journey with up to 4 train changes depending on which run you choose. Or, you can take the train to either Milan Malpensa or Pisa (Pisa is closer) and take a budget flight. www.skyeurope.com flies from Pisa and www.easyjet.com and www.click4sky.com flies from Milan Malpensa.