Can you please review my itinerary and/or give me transportation tips?

I entered your itinerary into the chart on RailSaver and it suggested a German Rail Twin pass for 2 adults traveling together for 4 days in one month which cost $430.00.

Link for the German Rail Twin pass:

http://ricksteves.raileurope.com/us/rail/passes/german_rail_twin_pass.htm

Go to this site and enter your itinerary. Enter Prague as Praha. Enter Interlaken OST.

Then print out the results.
http://www.railsaver.com/

According to Rail Saver:

Amsterdam to Berlin:

You should use the following combination of railpasses and tickets to pay for this journey:

Purchase a 2nd Class Adult City-to-City Ticket to cover the segment from AMSTERDAM to BAD BENTHEIM.

Use the German 4 Day 2nd Class Adult FlexiPass Companion/Saver to cover the segment from BAD BENTHEIM to BERLIN.

Berlin to Prague:
You should use the following combination of railpasses and tickets to pay for this journey:

Use the German 4 Day 2nd Class Adult FlexiPass Companion/Saver to cover the segment from BERLIN to DECIN.

Purchase a 2nd Class Adult City-to-City Ticket to cover the segment from DECIN to PRAHA.

Praha to Munich:

You should use the following combination of railpasses and tickets to pay for this journey:

Purchase a 2nd Class Adult City-to-City Ticket to cover the segment from PRAHA to FURTH IM WALD.

Use the German 4 Day 2nd Class Adult FlexiPass Companion/Saver to cover the segment from FURTH IM WALD to MUNICH.

Munich to Interlaken OST:

You should use the following combination of railpasses and tickets to pay for this journey:

Use the German 4 Day 2nd Class Adult FlexiPass Companion/Saver to cover the segment from MUNICH to SINGEN.

Purchase a 2nd Class Adult City-to-City Ticket to cover the segment from SINGEN to INTERLAKEN OST.

Interlaken OST to Paris:

Purchase a 2nd Class Adult City-to-City Ticket to cover this entire journey from INTERLAKEN OST to PARIS via LES VERRIERES.

Sounds like you will spend 5 of the 13 days on the train. Yikes!

Good lord, don't attempt this schedule. You'll experience nothing but trains. If your day in Amsterdam is the day you arrive, you have an evening in Amsterdam. Then a day on the train and an evening in Berlin. And so on and so on...

Thanks a lot for your input everyone! Regarding the travel time I understand what you are saying but we thought it to be manageable considering we hoped to take overnight trains and/or sleep on the train. From my research each train is between 4.5 to 6.5 hours which doesn't seem too bad.

By all means though I am fine with cutting out a stop or two. Paris and Interlaken are my must-sees and my friend's priorities are in Germany I believe. Perhaps we eliminate a German city and/or Prague? Ideally I would love to keep it all though. Anyone have any input?

I plan to travel every other day and only spend three hours in a car or train on travel days.

Your travel days include packing, checking out, eating, getting to the station, finding your train, making sure you get the right stop, finding transportation to your lodging, checking in, unpacking, eating. Even a three hour trip becomes a full day.

Using my rule of thumb, I map out a route and see how far I can get in my available time.

Berlin and Prague are the obvious choices to take out. They add a lot of travel time to your itinerary. I would probably make Munich/Salzburg the farthest Eastern point of your trip. Stop in Koln/Bonn, spend some time on the Mosel and/or Rhine or, alternatively, make some Romantic Road stops on the way to Munich.

Don't do it. The majority opinion seems to be that its very hard to get a decent amount of sleep on a night train... to which I concur. On a long trip, an occasional night train may save you some time, but on a short trip like this, you'll end up seeing less of your destinations because you'll be too exhausted. You also haven't figured in recovering from jet lag either, so you'll leave Amsterdam tired, and you'll arrive in Berlin not wanting to do anything but sleep.