I've done all three of those tours.
Although there are cathedrals (Padua, Siena, Assisi) on the Village Italy tour I don't really remember art museums. This is by far the most experience based RS tour I've taken. Lots of tastings...wine, honey, truffles, wine, lol! Being based in the smaller villages gives a really different feel from being based in the big cities of Italy. The only thing I didn't really like was for the CT, being based in Levanto. Of course it was rainy and end of season when I visited so perhaps that colored my thinking.
I loved Best of England which I just did in September. It was a mix of smaller villages (Stow-on-the-Wold, Conwy, Keswick) and bigger towns (Bath and York) and then London. I loved the history aspect of this tour and it was something I could connect with.
I am probably the only person in history that thought the Best of Ireland was just OK. Guide was very funny, bus driver was great, I just didn't click with Ireland. I am not a big drinker and don't really enjoy pubs. I found, unfortunately, that I don't really care for Irish traditional music. It turned out OK because the Trad music is in the pubs and doesn't start until late so I missed a lot of it by being an early to bed person. (Really, 930 or 10PM is about my limit, lol!!) I found the history of the Troubles and the continuing issues between the Republic of Ireland and Northern Ireland to be unsettling on a personal level. (We were there at the end of June, just as the folks in Northern Ireland were preparing for Marching Season.)
So, based on what you have already seen, I would suggest the Village Italy tour. Give yourselves an extra day in Padua up front. I didn't (went from Venice to Padua on the day the tour started) and realized there was a lot I didn't get to see. Give yourselves a day in Milan afterward if you are interested in another cathedral, lol. Transportation from Orta San Giulio where the tour ends and the Milan airports is slightly awkward. The guide will organize shuttles/taxis to Malpensa airport but don't get a really early flight out if you are leaving the day the tour ends.
For what it's worth, I did Paris and Heart of France this Fall too. Last year I did 21 day BOE so we've covered some of the same things.
Just my two cents! Your wants may be different than mine!