Thank you for all of the excellent suggestions. We have decided to slow our travel a bit. Here are our latest thoughts:
5 nights Madrid with side trips to Toledo and ElEscorial
5 nights Seville- Can we realistically day trip to Cordoba, Arcos, & Ronda or is this too much?
2 nights in Granada
We decided to cut out Barcelona and do that on our next trip. We like the idea of staying in fewer places, but would still like to see as much as we can with out overdoing it. Is it best to rent a car once we reach Seville or is it better to rely on public transportation? We drove through Tuscany and liked the flexibililty of a car. Your input please!! Also I would love any suggestions for moderate accomodations in these cities. We must get booked this week!