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How to get to Barcelona, spain from Lourdes, france?

Please help, thank you!! July 2008, I will fly to Paris, France, then take train to Lourdes, france, stay there 2 nights. then need to go to Barcelona, spain for 3 or 4 days. (But don't know how to get there, by train or bus?) , (can we buy ticket here?) after that, we plan to fly or take train from Barcelona to London, and stay at London for few days, then take train back to paris and stay there for 4 day. Should I get oyster card for stay at london? also, which railpasses should I buy? I got 16 days for travel , I hope I did not over do it. Any suggestion? thank you very much.