Zurich or Milan? Will be driving from Paris - October 2011 trip
Just two random city names? Why those?
Haven't been to Zurich, but there's enough in Milan to fill up two days. The Duomo (wander on the roof during the day, see it lit up at night), the Vittorio Emanuele Galleries, La Scala (tour + museum, or a performance), Castello Sforzesco and of course Da Vinci's Last Supper.
Where's your ending destination from Paris? These two cities aren't usually considered as top places to visit unless you're into banking and the opera.