Base for 5 nights in Switzerland coming from Varenna

Hello all, Looking for a suggestion on where would be a good base for 5 nights in Switzerland at the end of April/early May. We are coming from Varenna at the end of 3 weeks in Europe. We love train trips and will probably have a Swiss pass, although we don't want to spend all day on trains. There seem to be so many alternatives so I would appreciate any help.

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