02 Arena in London

Head over to http://maps.google.com. In the search box type inn "hotels near O2 Arena London" Looks like the the Holiday Inn express is the closest hotel. The Arena is very easy to reach via the Underground subway. The North Geenwhich station is right at the arena and the Jubilee Line take you there direct from the city center. IMO you are better of staying in central London and taking the Tube.

The arena's right by the North Greenwich (Jubilee Line, I think) tube station. There's not much out there of general tourist interest. I'd stay somewhere else. It can't be but about a twenty minute ride from central London. The Underground is simple. Walk in any station, chunk coins in the machine, buy a ticket, eyeball the route diagram, go. My kids were doing it alone before they were twelve and they're all pretty stupid, so it can't be that hard.

Another vote for public transport. (And in one of my favorite ways in which British English is a foreign language to US natives: "subway" in Britain is an underground pedestrian walkway, often a short tunnel under a street, and the underground train system known as the "subway" to a New Yorker, is called the "Tube" or sometimes the "Underground" in London. Go figure.) Anyway, I'm by no means the sharpest knife in the drawer, and I got the hang of the Tube system in London in a few minutes. With the Oyster Card, you just load up some money on it, and it works for both the Tube and the red London Transport buses. I'd pick a hotel with good Tube connections to O2 rather than whatever is in walking distance, which doesn't sound all that good anyway. Have fun!

It took me a little while to learn the Tube. I came from Paris and its amazingly easy-to-use Metro so that was part of my problem. Know what direction you need to go in (east, west, north, or south), pay attention to the signs, and take your time. If you mess up, get off at the next stop and backtrack. You'll figure it out and feel more confident after you do it.

Elsa, I agree with the others that it would be better to stay in a more central part of London and travel to O2 Arena via public transport. You may find it helpful to have a look at THIS Website. For example, the area around Victoria station is really nice. If you stayed there, it would be one stop from Victoria to Westminster (direction Upminster), and then transfer to the line that travels to North Greenwich station (direction Stratford). Hopefully the UK members here can correct me if my directions aren't accurate. The Tube is very easy to use, so that will be the easiest method. However, if you have a generous budget, simply hail one of the excellent London Cabs and they'll take you right to the Arena via the most direct and quickest route. Happy travels!

You can get a taxi there, but you might be lucky to get one after the concert finishes and several hundred other people are looking for a cab. Like everyone else here, I'd say stay in central London and use the Tube. It really is easy. I don't think I'd want to do a 15 minute walk at night through car parks etc to the Hoiliday Inn. I don't mean that it's a dangerous area, just that I wouldn't do that anywhere unless I had to.
Enjoy the concert! Who are you going to see?

I WANT TO THANK EACH ONE OF YOU WHO RESPONDED. IWILL BE GOING WITH MY BROTHER TO SEE IL DIVO, IT IS A BIRTHDAY AND CHRISTMAS PRESENT TO HIM. HE IS GOING THRU A VERY BAD TIME WITH HIS HEALTH AND I AM PRAYING THAT WE WILL MAKE IT . He has never been in London and I agree we will be better off staying in central London and taking the tube . This way he can see some of the sights there. I am from the New York area, I think I will be ok with the tube, You have given me a lot of information. Many thanks
Elsa