Prague 4 nights in July where to stay & see?

Prague is a great town and has a very good transportation system. Don't get overly concerned about your location. We stayed at the Roma Hotel and obtained a good rate thru czechbyclick.com. It's as few blocks from the Chas Bridge and directly on a tram line. Have fun.

Marriott Hotel - good central location

Guesthouse Lida is a great place to stay with a nice breakfast, and very helpful hosts.

I would make sure to see the Prague Castle area, walk the Charles Bridge (maybe walk up a tower or two), the Old Town Square with the Astronomical clock, Wenceslas Square for some shopping if you like, Havelske Trziste open-air market is a great place to pick up some souvenirs.

We just came back from staying at the Castle Steps in Mala Strana and we thought it was absolutely wonderful. But I agree -- public transport in Prague is such that location is pretty relative. I've stayed far out in the residential areas and still had only a 10-15 ride to get to the city center.

I enjoy the Hotel-Pav. It is reasonable, with AC, and a great buffet breakfast. Within walking didstance to all sights, plus tram goes to top of street. Don't miss a walking tour of the Jewish Quarter. Precious Legacy Tours does the best job. Ask for Zusanne. I look at booking.com to compare rates.

We also enjoyed our stay at Guest House Lida. It's a little away from the city center but near a tram line. There are good, inexpensive restaurants in the neighborhood.

We were there last summer and stayed at Guesthouse Lida; I would highly recommend it. The hosts were wonderful; they gave great recommendations for everything from restaurants to subways, and really know the city well. We had dinner at one of the places nearby and it was excellent and inexpensive; real local food and ambiance. Lida is located outside of the city center (that's part of why it was reasonable), but public transportation was very easy and it only took 10 minutes or so to get to the sights. The castle was great, and I agree with the person who recommended the Jewish Quarter; fascinating architecture and history (especially the cemetery).
Have a great trip!

My husband and I, along with 16 of his college students, just returned from a trip that included 3 days in Prague. We've travelled extensively, but Prague is our new favorite European city. The exchange rate is great, the people friendly and the view breathtaking! We would highly recommend Sir Toby's Hostel (sirtobys.com) It is very clean, quaint, a super helpful and friendly staff and is a few steps from the tram. Make time for the Jewish Quarter and a stop at the top of the hour at the Old Town Hall to see the Astronomical Clock.