We are looking to travel from Murren to the Dolomites/more specifically Cortina d'Ampezzo the end of May -- has anyone done this? Did you use trains and then rent a car at some point? We are flying into Geneva, spending a few days in Murren, and then wanting to do the Dolomites before flying out of Milan. I see you can drive through Liechtenstein and Austria but is that hard with entering counties/tolls? Should we go south by train right into Italy? Thank you!
One thing to understand that if you rented a car in Switzerland to drive to italy and drop the car in Italy there will be a very large drop fee because you cannot rerent a car in Italy with Swiss license plates. It has to be transported back to Switzerland and that expense has to be covered. You would need an Austrian vignette, although that is pretty minor, and the driver must have an International Driver's Permit. Not a biggee, go to AAA.
Here is what I would do. Take a train (multiple connections from Muerren) to Venice Mestre and rent a car there and then drive a couple hours north to Cortina. You could drop back at Venice if you wanted to spent time there, then take the train to Milan and Malpensa Airport. Or you could drive it straight to Malpensa Airport and drop it there.
Is this a non-negotiable route that you want? You're going to lose a full day of your short trip going between 2 places that are not close to each other. I responded to your thread back in March that had a different 6 night itinerary but you never responded back to me. If you're trying to do 6 nights between Murren + Dolomites + getting back to Milan to leave I would advise against it. Nothing against the Dolomites, but losing an entire really long day to get there doesn't make sense when you have so little time. I'd pick somewhere else in Switzerland to enjoy and gain back a day.