Hotel Room for family of 4

You might try booking.com to check what’s available for your dates. I see there’s a Radisson but no Marriott in Bern. I don’t remember seeing any American type hotels in Wengen.

Checking I see there are Best Westerns in both Bern and Wengen. Maybe someone can give you more info on the particular hotels. I remember staying in a Best Western in France and it was not typical of what you would find in a BW in US.

Thank you Margie.
I will give it another look.

As Margie said, use Booking.com to search for lodging for the dates you need and with your requirements: one room, 4 people, etc.
However, book directly with the hotel. There is a Best Western in Bern near the train station that is listed in the RS Switzerland book. My husband and I have reservations for that hotel in June.

Check into the Novotel and Ibis hotels, both of which are budget European chains. Ibis and Novotel both have hotels at the Bern Expo, which is just 4 miles and a 15 to 20-minute tram ride to Bern’s Old Town, or “Innere Stadt.” That is where you’ll find Bern’s central train station as well.

Thank you all so much for the additional responses.
Novotel and Ibis are my top choices so far and will research the Best Western. If Rick recommends it, then it is worth a shot. 😃

Any advice on Air BnB?

In general, American-style chain hotels like Marriott/Hilton/etc are less common outside the major business cities in Switzerland.
Rooms are usually smaller here and it can be difficult to find a city hotel room that takes 4 people - especially since your kids are older teens and not little kids, many places consider them adults for booking purposes and rooms often max out at 3 people. Novotel is ok, part of the French Accor group, more of a mid-range business hotel. The one in Bern is near the convention center (not an especially exciting area but not difficult to get to central Bern, about 8 mins by tram, free transport with hotel booking). You could look at something like Da Maurizio Suites or the related Max Aviation apartments - they are in a nice neighborhood full of embassies a little outside the historic center. Also takes about 7 minutes to get into central Bern via tram.
Family rooms are more common in the mountains, but if you would rather book an apartment, hopefully someone can suggest places available outside of the airbnb platform.