RE: But the percentage of people getting acute mountain sickness in Colorado seems too high (25-30 % ??). Elevation where most people get it (7 to 8 thousand feet) seems too low.
Mayo Clinic paper: http://www.mayoclinicproceedings.org/article/S0025-6196(11)63396-X/fulltext
Altitude-Related Illnesses
David L. Klocke, M.D., Wyatt W. Decker, M.D., Jan Stepanek, M.D
An estimated 30 million people are at risk for altitude related
illnesses in the western United States annually. Many cases are
unrecognized by the victims and by their physicians who may attribute
symptoms to viral illness, “hangover,” or fatigue. In addition,
commercial airline travel exposes passengers to a cabin pressure
equivalent of 2,500 m and allows them to travel rapidly to high
altitude destinations such as Aspen or Steamboat Springs, Colorado,
where they may be exposed to even greater altitudes. Approximately 20%
of tourists to Colorado ski resorts (elevation about 3,000 m) will
experience acute mountain sickness (AMS) in comparison with 67% of
climbers on Mount Rainier (elevation about 4,500 m). Approximately
0.01 % of tourists to Colorado ski resorts will experience the serious symptoms of high-altitude pulmonary edema (HAPE) or high-altitude
cerebral edema (HACE). In addition to AMS, HAPE, and HACE, other
medical problems may occur in low landers who ascend to high
altitudes, including peripheral edema, retinopathy, thromboembolism,
disordered sleep, high-altitude bronchitis,6 snowblindness
(ultraviolet keratitis), and exacerbation of chronic illnesses.