We are visiting Salamanca next April and are interested in a full day guided tour of wineries in the region. Any suggestions?
Are you asking if this is possible?
It certainly is if you hire a driver to take you to the various wineries in the Sierra de Salamanca:
https://rutadonfederico.com/sierra-wine-experience/
https://enoturismospain.com/search/ciudad-visitar-bodegas-en-salamanca