In Seville, we enjoyed staying at Apartamentos Suites Santa Cruz located in Barrio Santa Cruz, which is very centrally located and conveniently located to the Alcazar and the Seville Cathedral. The hotel's main office and reception desk is in Plaza de Dona Elvira, but the apartment is located in a different building at Calle Pimienta, about a block away. This is a pedestrian only area.
We rented a one-bedroom apartment with a kitchen. Even though we don't cook while on vacation, we wanted a spacious place to spread out for 4 nights.
My only complaint about Barrio Santa Cruz is that it is very crowded.
Unfortunately, the lovely hotel we stayed at in Granada is permanently closed.