Drive from Lisbon to Sevilla

Don't do it , drop charge on rental car is huge from renting in one country and dropping in another.

I assume you’re returning to Lisbon to avoid the large drop off fee already mentioned. You could go to Sevilla via Zafra. It’s about in the middle. On your return you could take the more southerly route west past Huelva into Portugal then turn north back to Lisbon. Either route will take 4 hours 45 minutes or so. There are tolls on the Portugal roads.

Going via Zafra, in the same area are Castle Nogales, Castillo de Feria s. XV, and Jerez de los Caballeros. It’s described as a very picturesque small town. The old town is surrounded by a Moorish wall with six gates.

Along the southern route in Spain is Niebla Castle and Dolmen de Soto.

jaimeelsabio, Thanks for the suggestions, sounds great! Will definitely look into it. Yeah it is a round trip.