Don't let the naysayers discourage you. I've been in Scotland in November, and sure, it gets dark early, and the weather could be iffy, but there is a multitude of things to do and places to visit. You didn't say how much time you have. If the kids are in secondary school or uni, Thanksgiving break is about five days. That doesn't give you a whole lot of time, so if that's the case, your activities would be pretty much limited to the Strathclyde region.
If you have more than five days, then you can venture farther afield. Unclegus has given some really good recommendations about Dundee. ("Oor Wullie - He's a'body's Wullie") In addition to what he has already mentioned, the city also has two world class universities and a thriving nightlife. Plus, I should add, Groucho's, the best independent record store in Scotland. (Sorry, Europa, your prices are too high!)
Anyway, Dawn, if you're seriously considering Scotland for a short break, come back to this forum, and we'll load you up with suggestions.