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Antwerp to Frankfurt. Best train route.

This April, we are ending a tour in Antwerp in the morning. We need to get to Frankfurt in the afternoon for another tour. Looking for advice on trains.

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My first look would be https://int.bahn.de/en
I see a departure every 2 hours beginning at 7:54 am with a single train change at Brussels Nord getting you to Frankfurt in 3 1/2 hours.