If you are doing Amsterdam, after the river cruise, you will be acclimated.
Ask the cruise director about transportation to your hotel -
The Centraal Station is and easy walk from the cruise ship docks.
We went on a river cruise in April and were limited to one piece of luggage per person plus carry-on so toting your bags to the train station is very easy.
I would recommend the Blue Boat canal cruise. It is close to the museums.
Get tickets to the Rijks and go there after you drop your luggage at the hotel.
Be sure to get the one hour guided tour - well worth the money.
Vondelpark is across from the Blue Boat dock if you want to wander in a park
Plenty of great places to eat nearby BUT
Highly recommend Martine's Table near the Red Light District.
It is close to the Centraal Station within easy walking distance.
It is a meal you don't want to miss if you can get reservations.
Get up EARLY and take the Thalys to Antwerp. You have to have reservations.
Then change in Antwerp for Ghent/ Brugges.
Thalys will cut your travel time.
Brugges can be done in a 1/2 day; might consider a stop in Ghent; return late.
Delft, Hauge, Maduradam.
May want to decide how much you want to see.
May also find this is another very busy day
Van Gogh and Anne Frank house.
Consider taking the train up to Zanse Shanse for some fresh air and countryside.
Since you already have Anne Frank tickets, you could do all of Day 1 on Day 4.
Use Day 1 to go to Zanse Shanse and perhaps Volendam or Enkheuizen.
We did not go to Van Gogh, went to Muller-Kroller instead; had a better representation of Van Gogh.
Just depends on what you like.
You have a pretty packed itinerary.
Pick and choose your activities carefully. No point in trying to run yourself ragged and cram in more than you can see just because it is there.
You will be back!