Are Visas required for Americans traveling to Italy in May 2025
Are you asking about the ETIAS? If so see the link below. The Fed 2025 update indicate it has not been activated. If you are scheduled for a tour later this year you can call the RS office for an update for your specific tour.
https://travel-europe.europa.eu/etias_en
Not if you're an American citizen intending to travel for 90 days or under. If you're referencing ETIAS (which is NOT a visa) there's no way to currently even apply for it.
If you are considering time in Venice in May, you may be required to pay an Access Fee depending on the days you will be there and whether or not you're staying in Venice or day tripping there.