I am heading to Rome this May, and recently found out that the day I had initially planned to do the Vatican is a Wednesday, which is the same day of the Papal Audience. I have read various contrasting reviews, some saying to absolutely avoid the Vatican Museums and Sistine Chapel on a Wednesday because the crowds are terrible, and others saying that while it is more crowded than other days, it isn't that bad and doesn't hinder your experience or create a situation where you miss seeing things.
Does anyone have experience with Vatican City on Wednesdays? For context, we will be there the last week of May.