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Vatican and Sistine Chapel tour?

My wife and I are doing the Best of Venice, Florence & Rome in 10 Days in October. We are tacking on a few days after the tour and want to use one of those days to go to the Vatican. Does anyone have a recommended early morning guided tour to take? We'd like to avoid crowds as much as possible.

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We did the Pristine Sistine by Walks of Italy and it was very good