“A good amount of time to spend in Venice to see the city.” A caveat, I am totally biased when it comes to Venice. Our first visit was for six days, our second visit was for six+ weeks.
You can tick the big sites in Venice, Doges Palace, the Basilica and a church or two in a busy day. But you won’t have really seen the city.
Getting a handle on Venice takes a bit of doing; the streets full of water, main routes that are a couple of metres wide, getting lost (and you WILL get lost).
It looks like you have five nights in Venice, and that is a good amount of time. It means that you can visit the second rank sites, many of which are more interesting and engaging than the so-called must see things. Check out, for example, the Querini Stampalia Foundation, or the Georges Cini Foundation on San Georgio.
You will use the vaporetto system, the waterbuses. (Once they were steamers, the name has persisted.) Download the app Chebateo (which boat). It links to the vap routes and timetables; every Venetian has the app. “If we scamper, we’ll make the 16:20 on route 4.1.”
And do get a paper map, costs about 3 euro from any tabac. Sure, everyone says that getting lost in Venice is part of the pleasure, but Google maps don’t cut it. We have spent about a year in Venice over some ten visits, and I still carry a very battered map.
Enjoy!