Traveling from Rome to the Cinque Terre

IMHO, there's no need to take a tour of the CT as it's easy enough to get around by train and ferry. This is not a day trip from Rome, however. You need to be able to stay at least one night to make it worth the effort, and given the travel time from Rome, I'd even consider two.

There are 5 villages so the time it'll take to get there depends on which one you want to stay in but it's a minimum of 4 hours from Roma Termimi to Riomaggiore (the southernmost of the 5) by train, 4 hours and 18 minutes to Monterosso (the most northerly of the 5), and you will switch trains at least once along the way.

It's going to be a very busy place in late May and accommodations fill well in advance so I'd put the hustle on making reservations. Monterosso is our fave of the 5 because it's the largest, has room to spread the crowds out and has the most hotels/restaurants.

CT is not a day trip from Rome if that is what you are asking nor does it lend itself to a tour from Rome. It is a collection of villages along the coast. You should think about spending a couple of nights in one of the villages and then hiking between one or two.

Not sure if you will find many who have taken this kind of tour in case you don't here are some reviews

https://www.walksofitaly.com/rome-tours/cinque-terre-tours-from-rome

Instead of traveling to Rome for a weekend, and wanting to spend a day in Cinque Terre, why not just travel to Cinque Terre for the weekend? You could fly in closer, say Florence or Pisa, and take the train in.

framer1053, it would be great if you'd jump in here with more info on your intentions (day trip versus staying in the CT)? Otherwise we may be giving you options you are not interested in.

Regarding the "Walks of Italy" tour that Jazz linked....
That company has an excellent reputation among RS posters who've taken their tours in other locations so I'm sure they'd do a good job. Still, the reason I wouldn't book it - or any other one-day tour from Rome - is this:

Traveling from Rome to Cinque Terre by high speed train, you’ll have a
full 6 hours on the ground.

The duration of that tour is 14 hours so you'd be spending 8 of those in transit for just 6 in the CT itself. Additionally, it skips Riomaggiore and Corniglia altogether and spends 3 of the 6 hours in just one village (Monterosso) for shopping and lunch. It would be so much nicer, IMHO, to have the flexibility to spend as much or as little time in any or all of the 5 as the spirit moves you versus be tied to a limited agenda? You can do an overnight for the price of the tour or probably even less, and be able to enjoy the golden hours when the day-trippers are largely absent.

This text about about Corniglia is also incorrect:
"To visit this tiny town you would have to climb 365 stairs, but from the water, you’ll get the best views without breaking a sweat."

While the “Lardarina” stairway is one way to access Corniglia - which doesn't have ferry service - it's not the only one. There are inexpensive little buses which run up and down the steep hill between the train station and the village. This tiniest of the CT 5 was a personal favorite of mine with two of the prettiest churches. :O)

Hello. In my opinion, 4 hours each way doesn’t make sense for a day trip. For me, I associate vacation with relaxation and rejuvenation, so I’d spend the long weekend in either Rome or CT. Certainly not both.

By comparison, we split a 9 day vacation between Rome & CT last year and it felt like the right amount of time in each city/towns.

However, to answer your specific question...
I would NOT recommend a tour in CT. Buy the train ticket and simply enjoy the freedom of doing whatever you want. It’s just 5 small villages with spectacular views and places to eat, hike & people watch.
Rick offers plenty of information about all 5 villages that you could reference as a “tour guide”.