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Travel to Macchia d isernia on Saturday

We are coming Fiumicino airport on Saturday morning time but We have 5 person with bags almost go want to Macchia d isernia? So please guide to us how is better travel with minimum expenditure?? Thank so much

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How will you get around once you get there?
You can get to Isernia by train from Rome. See the Trenitalia website for schedules.
Are you visiting family or staying at a hotel? They will be a good source of advice on bus travel. Google indicates bus routes between Isernia and Macchia.