Thanks for the responses.
Southam: Plane tickets booked months ago. This trip consists of 5 nights in Bologna; 10 nights in Valletta, Malta; 5 nights in Rome; return to California. So flying to Bologna is not an option for us.
Becky: Your experience would be ideal but only time will tell if the same holds true for us. Regardless, we will definitely enjoy our trip!
Alohalover: Have checked their site. We'll probably get whichever train is easier, hopefully non stop from Fiumicino.
Dario: Will keep that in mind. We may have to call the owner of the apartment and will need a working phone.
To all responders - thanks for your suggestions. We're experienced travelers in our 70s and coming from SFO, which means changing planes in Philadelphia, landing in Rome; either a direct train to Bologna or changing in Termini; taxi or bus to apartment. We're looking to make our arrival as easy and stress free as possible. Whether that means getting a SIM at Fiumicino so we don't have to worry about looking for a store in Bologna, taking a direct train vs changing in Termini, taking the bus vs taxi to the apartment, we won't really know until we land in Rome. What we do know is that being aware of all the options recommended to us makes us feel more prepared for whatever happens.
Thanks again.