We used the Vatican tour in April. It was very good for both me, who had some art history background, and my husband, who had none. Our tour guide, Simonetta, was knowledgeable and friendly. The tour lasted about 2.5 hours, plus the time we spent on our own in the Sistine Chapel. The museum was very crowded, but I think it helped to be part of a group. I'm not sure how long the line we skipped was, but we walked past it for about 15 minutes! Note: It is helpful to bring a printout of your reservation because the guards outside check it before you get into the quick entrance door. I had not brought ours because it did not say to, and the first guard told me I was out of luck. Ack! We asked another one and got right in. Once at the reservation desk they quickly brought up our reservation on their computer and everything was just fine after that quick scare.