Experience / recommendations for a 3-day car rental from the Rome airport?
We arrange our cars by calling up the broker Autoeurope toll-free [others use the web site]; get zero- deductible collision. Read this about driving in Italy [and about ZTLs, limited traffic zones]; avoid leaving anything of value in a vehicle when parked [and have an IDP]:
https://mominitaly.com/driving-in-italy/
For payment at toll booths see: https://www.autostrade.it/en/il-pedaggio/pagamento-al-casello
https://www.apathtolunch.com/2014/12/car-rental-company-reviews-for-italy.html
While Autoeurope is convenient, that convenience comes with a price -30-40% more. I've used Sicily by Car with great results, and far cheaper than the big rental brokers. You can also check Kayak for easy comparisons.