Hi Kevin,
Yes, your first night, you want to take it easy. Get acclimated around your hotel area. Enjoy a nice dinner and wine, espresso and a sweet or a flute of limoncello.
I arrive about lunch time in Rome. I get my bag. Go to catch my reserved shuttle and off I go to the city centre. I arrive just around check-in. I settle in. Unpack and organize. Shower and Dress, and I am off to dinner. Returning, I browse a bit on my Kindle until I am sleepy. I get a good night's sleep.
Check out the "Walks Of Italy" Welcome to Rome: Twilight City Stroll
https://www.walksofitaly.com/rome-tours/welcome-rome-walking-tours/
If you look at the itinerary, perhaps you can customize one of your own using the model itinerary they offer.
Also, if your time allows, check out this video by Pro Walks for more ideas -- https://www.youtube.com/watch?v=vK928kqYUPI -- A Rome Walking Tour. He has a lot of Italy videos. He holds the camera steady. No loud background music -- just the sights and sounds of normal Italian life with locals and visitors. It can be fun to watch.
Rome is absolutely beautiful -- a walking outside museum. Around every corner seems to be a surprise. Hope you will love it.