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Never traveled with portable oxygen before

Maybe this is a crazy idea so I'm looking for a better suggestion. This is our first trip to Italy using oxygen and I want to make it less stressful for my husband. After 6 days we plan to travel from Sorrento to Orvieto. I'm thinking it would be easier to just take the bus to Rome putting our luggage underneath and once we arrived at the train station in Rome I think we would have a choice of taking a bus or train to Orvieto. At this point I don't think the train would be a problem because it's direct to Orvieto. Three days later we will head to Florence...I feel a direct train would be best. Trip will be in Sept.

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