hey markelpatel
when do you plan on taking this vacation, how many days and what is your budget in euros?
hotels are difficult to find a family room for 5, you'll need 2 rooms and an adult in each room. an apartment is more likely for you and family, more space, kitchen to store some drinks and snacks, find one with a terrace to relax.
you can only move so fast as your children can. how much luggage, elevator/lift, stairs to climb up, arrival and departure times, can you store luggage if too early for check in and if not do you store at train stations or is there baggage storage somewhere. pack light, maybe find an apartment with washer/dryer, in summertime it's hot, sticky, crowded, lots of waiting in lines, does place have A/C? any important sites you wantt to see and train connections, book early for cheaper fares, where are you flying from and does anyone have problem with jetlag, how many nights on the ground, takes about half day or so to move from place to plave. wake up, pack, get ready, walk/run to train: check into next place, unpack and get situated. if you have a car, get an IDP, if parking, where and how much and distance to hotel/apt, no driving in main cities because of restrictions, getting tickets to pay expensive fines later.
lots to think about with a family. when you have done your research, get a guide book, decide what's important to see, how tired will the kids be, how many museums, art, monuments, churches do you want to sightsee with them, come back and these posters will give you the good bad and ugly.
aloha
aloha