First, thanks to all for postings - extremely helpful via searches!
Going Oct 17 - 25, EWR to FCO direct
So far, we've reserved at iq hotel except for last night at Hilton FCO (great suggestion from forum members)
We reserved with the Roman Guy for Colosseum, Vatican and a day trip to Florence (Accademia walk)
Other days - we just like to walk around like the Forum area and some of the other neighborhoods.
Weather looks good - perhaps someone who has been mid to end of October could weigh in
Our nieces went last spring and had a great time - looking forward to meeting the locals and fellow travelers.