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Getting from Rome to Ascoli Piceno?

What's the fastest way to get to Ascoli Piceno from Rome (and back?)? I'm thinking a bus or train but all I can find online is a bus with stops that takes over 5 hours. Is this right? Thanks!

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Shannon,

Enjoy your trip!

EDIT: Here is a list of where you can purchase bus ticket in Italy, there is a photo of the storefront in Rome @ V. Castro Pretorio
(top right of screen) : http://www.prenotazionistartcardinali.it/rivendite.php