From Venice Airport (VCE) to Venice City

https://search.ricksteves.com/?query=Venice+transportation&button=

This is a frequent topic here. You can also ask your lodging for their advice.
Have a wonderful trip!

From a frequent poster:
Getting to Venice from Marco Polo Airport. [Make sure you have seats on the right/starboard side of the aircraft, for a view of Venice as you fly into Marco Polo.]
Do take a look at your hotel website – there may be info there. Otherwise,
Water taxi will get you close, maybe to, the door of your hotel. Can carry about ten people, will cost about €140 for the boat. No need to book, taxis are waiting at the Marco Polo dock.
Shared water taxi. Minimum of two people. Book in advance, wait at the desk in the terminal for the others sharing the taxi. Costs about €30 per person. Google “shared water taxi Venice”, use the venicelink dot com web site. Will get you to a vaporetto stop near your hotel.
Alilaguna ferry, as per below.
Bus to Piazale Roma, then walk to your hotel, or take vaporetto to the nearest stop. Buses leave from the outside the terminal, tickets at the machine.
Water transport in Venice.
1. Gondolas. Only for pleasure, not for transport. 90 euro for half an hour for the boat, more for evenings.
2. Traghetto – big gondolas, two oarsmen, about ten passengers, for crossing the Grand Canal. Found at Rialto, San Toma and a couple of other places. Cost 2 euro per trip, can save a heap of walking.
3. Water taxis, which are like a floating limo, costs to match.
4. Vaporettos - ACTV. Are like a floating bus, operate on a bunch of routes. Get the app Chebateo for routes and schedules. Vaps do not service the airport. Vaps are not water taxis.
5. Alilaguna ferries, service the airport, run from Marco Polo via a bunch of stops to the main part of Venice, Murano and Lido. They stop at some, but by no means all, vaporetto stops.M

crucial to be able to gert what is best for you is to know which hotel you're planning to be in.

As said above, check the hotel website. It is rare for a Venice hotel not to have a "Find Us" or similar named page on their site saying which is the nearest vaporetto stop, Alilaguna stop, if they have a water gate, walking from the stops, probably a map... etc.

Also how many is "we"? Any special walking needs, etc.?

The shared water taxi has worked well for us when we have stayed near San Basilio.

The best way, in my opinion, is as follows.

From the airport, take the ATV bus # 5 (or a regular land taxi) to Piazzale Roma, and then the vaporetto to the stop closest to your hotel. Then just walk to the hotel. If you supply the name of the hotel we can probably give more specific directions. The hotel web site may also have some detailed instructions.

You can get a vaporetto pass at the airport for the number of days you'll be there and can also add a one or two way bus ticket. I think you can still do it on line from home, print out a voucher, and turn the voucher in for the pass at the airport. Just make sure to validate the pass every time you take it or the bus to P. Roma.

We've done the above a number of times. Easy-peasy! Have a good trip.

How many is ‘we’? We were 4 and the water taxi worked well for us. Not the cheapest but fast, right to or very near the accommodation and a nice way to approach the city.